Quote from Adrian Monk in Mr. Monk and the Red Herring
Dr. Kroger: Adrian, you were lucky to know her. And I know you'll always be grateful, but it's time for you to move on. You've gotta start looking for your new assistant. Adrian Monk: Impossible. Dr. Kroger: Yeah, well, that's what you said before you found Sharona. But, Adrian, you've got to start looking. Your new assistant is out there somewhere. Adrian Monk: God help her.