Quote from Frasier in No Sex Please, We're Skittish
Frasier: Niles, Julia and I have never been together sexually. Look what happened with Roz. We slept together two ago, she's still suffering. [Niles gives Frasier a quizzical look] In the sense of pining! Niles: Well, Frasier, you don't really suppose that after one night Julia- Frasier: Oh, open your eyes, Niles! It's the same scenario: an infatuated co-worker, a night of passion. What if things don't work out between us? Every day she'll be forced to stare through the glass at me. Wondering what might have been, until one day, like Roz, she goes mad! Niles: Um... I'm leaving now. Can I pick you up anything on Earth?