Quote from Niles in Frasier's Curse
Daphne: Am I glad you're home. Martin: What's wrong? Daphne: It's Dr. Crane. Ever since he came back from his job interview he's seemed awfully depressed. In fact, he's as bad as I've ever seen him. Niles: Oh, I guess it didn't go well. Daphne: I gather not. He mumbled something about it being worse than the Dresden premiere of Schumann's Second Symphony. Niles: And you left him alone?! [running] Frasier! Daphne: He's in the kitchen. [finding Frasier with his head in the oven:] Niles: Oh, my God!