Quote from Niles in The Show Where Sam Shows Up
Sam: This is strange. I gotta tell you, I didn't know he had a brother. Niles: Frasier, I don't mind telling you I'm a little offended that in all the time you spent swapping bon mots with the beer-nut set, you never once mentioned you had a brother?! Sam: Well, you know, the truth is, I bet he said something. It's just that when Frasier gets going you kind of have to tune him out. Niles: That's a good slogan for his radio show. "Dr. Frasier Crane: when he gets going, you have to tune him out."