Quote from Roz in The Guilt Trippers
Roz: And when I think about this trip to Wisconsin, I just dread going without Roger. My family thinks I'm a total loser as it is. Now I'm just going to prove them right. "Roz is a failure at love." "Roz can't find a man." Frasier: They don't really say that, do they? Roz: Oh, you haven't met my perfect sister, Denise. I mean, I love her and everything, but she's a total bitch.