Sheldon: So, listen, I have a secret that I need to tell someone. But you can never say a word. Not even to Howard.
Bernadette: I'm your girl. Lay it on me.
Sheldon: Really? You keep things from your husband?
Bernadette: No, I tell him everything. Don't be a child.

Howard: I'm sorry I didn't take you to the airport. I just want you to know I'll never forgive myself for being so selfish. And I promise to keep you close for the rest of my life.
Bernadette: Oh, no, that thing's gonna end up in my bedroom.

Bernadette: (Shouting from the bathroom) How many times do I have to tell you to replace the toilet paper when it's empty?
Howard: I'm in the middle of something.
Bernadette: So am I!

Bernadette: Gosh, Amy. I'm sensing a little hostility. Is it maybe because like Sheldon's work, your sex life is also theoretical?

Penny: Look, I know this is your wedding, and you can do whatever you want, but if you think anyone but me is gonna be your maid of honor, then you're an idiot because you are my best friend.
Howard: Too late, Bernade-
Amy: (pushes Howard out of the way, rushes to hug Penny) Bestie!

Sheldon: Did Bernadette even try to send us a sewing kit?
Amy: She did. Amazon, standard shipping, not even Prime.
Sheldon: (gasps) We could've done that ourselves.
Amy: (chuckles) That's what she said.

Amy: Okay, what's the next test?
Sheldon: Loyalty. We need to choose someone who has our backs, someone who will keep our secrets even from each other.
Amy: Well, I don't have any secrets from you. Do you have secrets from me?
Sheldon: Yes. Oh, that has been weighing on me for years.