Leonard: Okay, well, if you really want to know, I'll tell you where I was. I was at Wil's D&D game, but that's all I can say.
Penny: Oh, fun. Were there famous people there?
Leonard: Ah, sorry, I-I-I can't tell you that. Okay, well, yes, but I-I-I-I can't tell you who.
Well, no, I-I can tell you Shatner, but that's only because you already knew that one.
Penny: Well, I'm glad you had fun.
Leonard: Yeah. Ugh, I wish I could tell you who else was there. [chuckles] I can't, I promised.
Penny: Yeah, if it makes you feel better, I couldn't care less.
Leonard: That's true, you don't care, so there's no harm in telling you.
Penny: Okay, you really don't have to.

Sheldon: Woman, you are playing with forces beyond your ken.
Penny: Yeah, well your Ken can kiss my Barbie.

Raj: [to Amy] If you were having Sheldon's baby, would you really want him in the room?
Penny: Yeah, if he's in the room when they're making the baby, I'll give you $10.

Penny: I mean, who even reads Scientific American?
Leonard: It's kind of a big deal.
Penny: If it's such a big deal, how come the biggest celebrity they could get for the cover is a molecule?

Wil Wheaton: All right, Professor Proton fans, get ready to meet Dr. Sheldon Cooper and Dr. Amy Farrah Fowler, a pair of real-life scientists who may win the Nobel Prize. That's like the Kids' Choice Award, but with more science and less slime.

Sheldon: Kids' Choice Award? Why would they let kids choose anything? They're basically human larvae.
Wil Wheaton: Well, they are kind of our target audience.
Sheldon: Greetings, children. Toys, am I right?
Amy: He is. He has hundreds of them.

Amy: Okay, imagine you're looking in a mirror. The image you see looks just like you. That's called symmetrical.
Sheldon: Now imagine you have a billion mirrors, and each of them reflects one thing about you correctly and a billion things about you incorrectly. And imagine the set of incorrect things are floating in an abstract n-dimensional hyperspace. Now imagine there was never a mirror to begin with.