Amy: Sheldon, I know you're upset about the paper, okay. I'm upset, too.
Sheldon: I mean, I was so sure we were right. Every fiber of my being felt like this was it. This was the one. How can I trust my instincts anymore?
Amy: Well, just because our theory was wrong, that doesn't mean you're wrong about everything.
Sheldon: Doesn't it? I've always thought I hated jazz, maybe I was wrong. Maybe it's great to hear all the notes at once. [music plays] I'm trying, I'm really trying!