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Quote from Sheldon in the episode The Conjugal Configuration

Sheldon: Is it possible that you're sexually frustrated?
Amy: Okay, now I'm testy.
Sheldon: If you had adhered to my coital schedule, your brain would be floating on a sea of oxytocin right now.
Amy: Don't talk to me about my brain. I'm a neurobiologist.
Sheldon: Then you should know the benefits of the special hug that grown-ups give each other.
Amy: Sheldon, everybody's listening.
Sheldon: Of course they're listening; we're interesting.

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