Donny: What's the difference between a blister and a boil?
Daphne: Donny!
Donny: God, I took my shoe off and it was like I was growing another ankle bone down here. Doc, you went to med school, what am I supposed to do with this? Lance it or something?
Niles: Oh, well, I. You know, as I recall the best thing for that would be to soak it in tepid water for at least half an hour.
Donny: All right. What luck, huh. Can you imagine a worse could have happened to me on the night before my wedding?

Mel: Niles?
Niles: Darling.
Mel: I was just looking over these brochures for our honeymoon. Hi, Daphne. [To Niles] Now, the Denali has a step-down tub, but the Greeley has the most romantic view of the Grand Canal. What do you think?
Niles: I think a woman with your exquisite taste can handle this decision.
Mel: [to Daphne] Oh, he says that now. Wait 'til the honeymoon's over.

Frasier: Well, actually it's been delayed a bit. You see, the justice of the peace started out asking the witnesses to step forward, and three of Daphne's brothers just ran off into the woods.

Niles: Dad, where did Morrie keep this?
Martin: In his wine rack.
Frasier: Which is...?
Martin: In the boiler room.
Frasier: Oh, lord. I'll just save this little treat for later.
Niles: Yes, well, thanks for the thought.

Mel: Does anybody besides me feel like a cup of coffee?
Frasier: Oh, I'll brew a pot.
Mel: Oh, don't be silly. I've been here enough times to know how to get the coffee made. Daphne, make us some coffee. ... kidding.

Daphne: You know, Mr. Crane, Eddie seems awfully fidgety. I don't think he got enough exercise on that walk.
Martin: Anybody needs any exercise, it's you, the way you're eating now. You know, when they put "Party Size" on that cookie bag, they don't mean party of one.